1. Drug Name:

maropitant citrate

2. Brand Names:

Cerenia

3. How Dispensed:

Prescription-only

4. Forms:

16, 24, 60 and 160mg oral tablets

10mg/mL injectable solution

5. Drug Type/Class:

Neurokinin (NK₁) receptor antagonist antiemetic

6. Uses in Dogs and Cats:

Indicated for the prevention and treatment of acute vomiting in dogs and cats. Labeled for prevention of vomiting due to motion sickness and to control vomiting secondary to chemotherapy in dogs. Cerenia has also been shown to decrease visceral pain (pain related to the internal organs).

7. How it Works:

Cerenia works in the central nervous system to inhibit Substance P, which is a key neurotransmitter (a chemical substance that is released in the nervous system) involved in vomiting.

8. Side Effects and/or Signs of Overdose:

Side effects are rare but include diarrhea and decreased appetite. Vomiting and hypersalivation may be seen if giving higher dosages, which are required to prevent motion sickness. Swelling or pain at the injection site has been seen with the administration of the injectable form.

Cerenia is well tolerated so issues with overdosage are unlikely, but may include vomiting. Acute overdosage is unlikely to cause serious clinical effects.

9. Drug Interactions:

None currently reported

10. Cautionary Statements:

• Use with caution in dogs with liver dysfunction
• Do not use in puppies less than 8 weeks old or kittens less than 16 weeks old as it may cause bone marrow suppression
• The safe use of Cerenia has not been evaluated in dogs used for breeding, or that are pregnant or lactating

Read more:

Your Complete Guide to Vomiting in Cats

Vomiting and Diarrhea in Dogs

Gastrointestinal Diets for Dogs and Cats

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