It’s important to understand a medication’s uses and side effects before giving it to your pet. This medication info sheet is meant to give you a good understanding of what Onsior (robenaxocib) is used for, how it works, and potential side effects in cats and dogs. Always consult a veterinarian before giving your pet any medication.
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Robenacoxib
Onsior
Prescription-only
5mg, 6mg, 10mg, 20mg, 40 mg tablets
20mg/mL injectable solution
Non-steroidal anti-inflammatory drug (NSAID)
Onsior is used to control pain and inflammation that is associated with surgery and musculoskeletal disorders such as osteoarthritis and fractures.
Robenacoxib blocks the enzyme (protein that increases the rate of a chemical reaction) cyclooxygenase (COX-2). Blocking this enzyme decreases the production of prostaglandins that causes the pain and swelling of inflammation and other conditions. Inhibiting COX-2 provides anti-inflammatory, pain relief, and can decrease fever.
Gastrointestinal side effects are common and can occur in 10% of dogs and cats. These side effects include vomiting, soft stool to diarrhea, decreased appetite, and blood in the stool. Some pets may have a decrease in energy levels. Elevated liver enzymes are common in dogs on long-term robenacoxib.
Overdosage can cause gastrointestinal upset and adverse effects on the kidney. Gastrointestinal ulceration can occur which can cause perforation (development of a hole) in the stomach or intestine. This can lead to infection and inflammation in the abdomen (peritonitis) or throughout the entire body (sepsis).
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