trazodone
Desyrel, Oleptro
Prescription-only
50mg, 100mg, 150mg, 300mg tablets
Used in pets to treat short-term anxiety concerns. This is especially helpful for post-operative recovery, to keep the animal calm and relaxed. Trazodone is also used for travel anxiety and noise phobias.
Trazodone increases serotonin levels in the brain. Serotonin 2A antagonist/reuptake inhibitors limit the brain’s ability to remove serotonin, causing serotonin to last longer. The more serotonin animals have in their brains, the less anxiety, obsession, and fear they have.
Limited side effects. Rarely see aggressive food-seeking, increased drowsiness, nausea, and GI upset. Signs of overdose include ‘serotonin syndrome’ (elevated heart rate, shivering, dilated pupils, respiratory distress, hyperthermia, and/or high blood pressure).
Aspirin and other NSAIDs, azole antifungals, Cisapride, CNS depressants, diuretics, fluoroquinolones, SSRI / Tramadol (increased risk of serotonin syndrome)
Not recommended for pets sensitive to MAO inhibitors. Use caution with severe heart disease or liver and/or kidney impairment. Do not use in pets with angle-closure glaucoma.
Noise Anxiety in Cats and Dogs
Preventing Separation Anxiety: How to prepare your pet for time alone after your COVID-19 quarantine
Click here to schedule a video consult to speak to one of our vets. You can also download the FirstVet app from the Apple App Store and Google Play Stores.
Book a video consultation with an experienced veterinarian within minutes.