Pet Medication 101: Tylosin

1. Drug Name:

Tylosin

2. Brand Name:

Tylan

3. How Dispensed:

Prescription-only

4. Forms:

Powder Form 2.5grams/teaspoon; may be formulated into various strength oral capsules, Tylan-200 Injectable 200mg/ml, Tylan-50 Injectable 50mg/ml

5. Drug Type/Class:

Macrolide antibiotic

6. Uses in Dogs and Cats:

Tylan is used to treat colitis, intestinal bacterial overgrowth, soft tissue infections caused by beta-hemolytic streptococci, and pulmonary infections caused by mycoplasma pneumonia in small animals. It is effective against Gram-positive microorganisms, Gram-negative microorganisms, Mycoplasma, and spirochetes. It has also been used to prevent tear stains in small dogs.

7. How it Works:

Tylosin is bacteriostatic and inhibits bacterial protein synthesis by inhibiting the 50S ribosome.

8. Side Effects and/or Signs of Overdosage:

Side effects include pain and inflammation at the injection site, gastrointestinal upset, anorexia, vomiting, and diarrhea.

9. Drug Interactions:

Drug interactions with Tylan are not well established, but it should be used cautiously with digoxin, azole antifungals, cisapride, chloramphenicol, clindamycin, diltiazem, verapamil, omeprazole, sucralfate, warfarin, bromocriptine, buspirone, carbamazepine, chemotherapy drugs, cyclosporine, methylprednisolone, and theophylline.

10. Cautionary Statements:

Tylan should never be given to horses. Avoid using it in pregnant, lactating, or breeding pets. Use caution in pets with heart disease, kidney disease, or liver disease.

Read more:

Diarrhea in Cats 101

What Causes Bloody Diarrhea in Dogs?

Caring for Pets with Pneumonia

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