Pet Medication 101: Metoclopramide

1. Drug Name:

Metoclopramide

2. Brand Name:

Reglan, Maxolon, Clopra, Octamide, Reclomide

3. How Dispensed:

Prescription-only

4. Forms:

Tablets 5mg, Tablets 10mg, Syrup 5mg/5ml, Injectable 5mg/ml

5. Drug Type/Class:

Gastrointestinal prokinetic, anti-emetic (anti-vomiting medication)

6. Uses in Dogs and Cats:

Metoclopramide is used to treat nausea, vomiting, and acid reflux.

7. How it Works:

Metoclopramide promotes gastrointestinal movement of the stomach and upper small intestine. By helping food pass quickly through the upper digestive tract, Reglan prevents reflux of food and acid from going back into the esophagus.

8. Side Effects and/or Signs of Overdosage:

Side effects include restlessness, hyperactivity, spasms, twitching, drowsiness, constipation, increased urination, abdominal pain, dizziness, diarrhea, and confusion.

9. Drug Interactions:

Reglan increases gastrointestinal activity and affects the absorption rates of many oral drugs. Your pet may have adverse effects when taking multiple medications.

In addition, Reglan may react with acetaminophen, anticholinergic medications, anticoagulants, anxiety medications, aspirin, atropine, CNS depressants, sedatives, cimetidine, cyclosporine, tetracycline, diazepam, digoxin, insulin, MAOIs, muscle relaxers, and narcotic pain medications.

10. Cautionary Statements:

Avoid using metoclopramide in pregnant or nursing pets. Avoid using Reglan in dogs with a history of epilepsy because it can cause seizures in these pets.

It is not safe to use Reglan in pets with GI/stomach/intestinal obstruction, bleeding, hemorrhage, or perforation. It should be used with caution in pets with diabetes, kidney disease, and hypertension.

Read more:

Your Complete Guide to Vomiting in Cats

Vomiting and Diarrhea in Dogs

Parvovirus in Puppies: A Treatment and Prevention Q&A

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