It’s important to understand a medication’s uses and side effects before giving it to your pet. This medication info sheet is meant to give you a good understanding of what Proin (phenylpropanolamine) is used for, how it works, and potential side effects in cats and dogs. Always consult a veterinarian before giving your pet any medication.
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Phenylpropanolamine (PPA)
Proin, Propalin, Cystolamine, Uricon, Uriflex-PT
In the US, Proin is a prescription and veterinary use only medication. It is no longer produced for human use.
Be sure to follow your veterinarian’s instructions for administration and cautions as these will be tailored to your specific pet.
Liquid or tablet (can be chewable tablet as well) of 25mg, 50mg and 75mg
It acts fairly quickly and takes effect within 1-2 hours.
Sympathomimetic – imitates the sympathetic or “Fight or Flight” system
Used to treat urinary incontinence due to poor muscle tone in the urethral sphincter
Proin acts on receptors that cause typical “Fight or Flight” “fear” nervous system response, causing the bladder outlet sphincter to tighten, increasing heart rate and blood pressure
Serious Side Effects:
Since bladder control comes from the nerves in the pelvic area, some pets can be helped by veterinary chiropractic adjustment without the need for worrisome side effects and monitoring. See our article about Veterinary Chiropractic as well as Acupuncture.
Why does my pet need a urinalysis?
Urinary Tract Infection (UTI) in Dogs
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